Oral Tren Use/Dosing and Side Effects
 

I found this article on Oral Tren thought I'd put it up:

Note the extremely high Anabolic/Androgenic Ratio: approximately 12 000/6 000 (test E is 100/100).


Pharmaceutical Name: Methyltrienolone
Chemical Structure: 17beta-Hydroxy-17-methylestra-4,9,11-trien-3-one
Chemical Formula: C19H24O2
Molecular Weight: 284.3974
Active Life: four to six hours
Anabolic/Androgenic Ratio: approximately 12 000/6 000
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Methyltrienolone is essentially the same compound as trenbolone, but with the addition of 17 alpha alkylation, allowing it to remain active after oral administration.


In simple terms, methyltrienolone offers all the advantages of trenbolone in an orally active form. However, the increased benefit comes with a significant price in terms of hepatoxicity, as demonstrated below.


Similar to trenbolone, methyltrienolone has a remarkably strong binding affinity for the androgen receptor, even surpassing that of testosterone.


This supports the claim that trenbolone is highly anabolic. As binding to the androgen receptor activates the anabolic mechanisms responsible for muscle growth.


Androgen receptors are also present in adipose tissue, and when stimulated by compounds like Tren Oral. They can promote higher-than-normal lipolytic action (1).


This means that the drug not only helps to build muscle, but also aids in fat burning.


Another distinctive characteristic of methyltrienolone is its anti-catabolic abilities. By binding with receptors that interact with glucocorticoid hormones, which are catabolic hormones (2), methyltrienolone can inhibit cortisol and other catabolic hormones in the body.


This makes it ideal for users aiming to reduce body fat. As the compound helps minimize muscle wasting when running a calorie deficit.

Oral Tren Use & Dosing

Oral Trenbolone was originally developed by a French pharmaceutical company, but never commercially produced due to its severe hepatoxic effects. This indicates the true harshness of the drug.


Therefore, users should exercise caution and limit their cycles to short periods. Excluding other highly hepatoxic steroids like 17 alpha alkylated oral steroids.


For cycle duration, most users limit themselves to four weeks or even shorter. Any extension of this time requires continuous blood tests by a doctor, regardless of the planned duration. Individual response and liver function should also be considered.


Regarding dosing, since little research has been conducted on Oral Tren, anecdotal information guides the dosage recommendations.


Normal doses of Oral Trenfor males range from 400-800 micrograms. Females are not advised to use this drug.


Higher doses have been reported, but this increases the risk of negative side effects, including temporary liver conditions like jaundice. Users should be cautious when starting or increasing the dosage.

Oral Tren Side Effects/Risks

Methyltrienolone, similar to trenbolone, does not exhibit estrogenic activity, thus alleviating concerns about estrogenic side effects. However, it is important to note that Oral Tren is highly androgenic and may result in side effects such as prostate enlargement, oily skin/acne, and potential hair loss.


Due to its androgenic nature, women are strongly advised against using this compound as it can lead to virilizing effects.
While methyltrienolone lacks estrogenic side effects. It functions as a progestin and can bind to progesterone receptors, potentially causing breast growth and lactation. Additionally, methyltrienolone can enhance estrogenic side effects caused by other aromatizing drugs. To mitigate these effects, users can consider using ancillary drugs like:

• bromocriptine,
• vitamin B6,
• cabergoline, or letrozole to lower prolactin and progesterone levels.

Trenbolone Oral, being a progestin, has a significant impact on natural testosterone production. Similar to trenbolone and nandrolone, methyltrienolone can suppress testosterone production for an extended period. To avoid sexual dysfunction, libido problems, or mental side effects associated with low testosterone. It is advisable for users to combine testosterone with Oral Trenbolone , even during short cycles.


While some animal studies suggest that methyltrienolone may increase libido in certain cases, others have shown the opposite effect. Thus, testosterone supplementation is recommended as a precautionary measure.


Notably, the company that originally developed Oral Tren deemed it too hepatotoxic for commercial human use.


Methyltrienolone is particularly harsh in terms of hepatoxicity, leading to elevated liver values with moderate use. Liver damage should be considered a significant risk if doses or duration of usage exceed accepted standards or if the user has existing liver abnormalities.


Therefore, concurrently using other 17 alpha alkylated steroids with methyltrienolone, or using them around the same time, is a risk that should be avoided.

Helpful Links

Trenbolone Enanthate vs Trenbolone Acetate

References

1. Sjogren J, Li M, Bjorntorp P. Androgen hormone binding to adipose tissue in rats. Biochim Biophys Acta. 1995 May 11;1244(1):117-20.

2. Ho-Kim MA, Tremblay RR, Dube JY. Binding of methyltrienolone to glucocorticoid receptors in rat muscle cytosol. Endocrinology. 1981
Nov;109(5):1418-23.

3. Lax ER, Baumann P, Schriefers H. Changes in the activities of microsomal enzymes involved in hepatic steroid metabolism in the rat after administration of androgenic, estrogenic, progestational, anabolic and catatoxic steroids. Biochem Pharmacol. 1984 Apr 15;33(8):1235-41.

4. Dube JY, Tremblay RR, Chapdelaine P. Binding of methyltrienolone to various androgen-dependent and androgen-responsive tissues in four animal species. Horm Res. 1976;7(6):333-40.

5. Sodersten P, Gustafsson JA. Activation of sexual behaviour in castrated rats with the synthetic androgen 17 beta-hydroxy-17 alpha-methyl-estra-4,9,11-triene-3-one (R 1881). J Endocrinol. 1980 Nov;87(2):279-83.

6. Baum MJ, Kingsbury PA, Erskine MS. Failure of the synthetic androgen 17 beta-hydroxy-17 alpha-methyl-estra-4,9,11-triene-3-one (methyltrienolone, R1881) to duplicate the activational effect of testosterone on mating in castrated male rats. J Endocrinol. 1987 Apr;113(1):15-20.

That was very informative CC. I think this shoube BUMPED! I dont know if its just me but i wasnt aware of the low estrogenic side effects can happen if its highly androgenic. Something to keep in mind, no one wants Gyno!

Great read bro, everyone needs to keep in mind with oral aas is the toxic attack on the liver and must take a liver support!


God Bless
Chris

I don't know of many sponsors that carry oral tren Naps did but the reviews were hit and miss

Good read. Everyone is raving about this stuff!

It's good stuff but you have to be careful with it

oral tren and test c
 

ive got the oral tren ordered (bulk order) I also ordered test c

so running the ot at 750mcgm a week for 4 weeks what should i run the test c at and how long

ill be taking liv 52 also

make sure you work up to the 750mcg, don't start it all in on go.
Test you can do at a low dose of 250mg, personally I prefer 500mg
I would do the test for 10 or 12 weeks and make a decent cycle out of it

damn im going to be a little short on the test c, ill have 2000mg BUT i do have 3000mg of primo, 12 ml (12 ampules) of omandren and 9 ampules (9 mls) tren a injectable

so what is the best way to use this?

CC i trust your advice
thanks

Hey BTW CC do you have your pic posted online somewhere

You could run the Omnadren for 6 weeks at 500mg.
I wouldn't waste the Primo on this one.

Hey olddog. Yeh if your going to run it get more primo for good results like CC said 20weeks id need 100ml of primo at 500mgs a week so ud want to start saving up lol a good option if u want to do a cycle soon but cant get primo now would be do the test for 15-20 weeks (i think 20 weeks is by far a better way to go) and get some EQ (Boldenone Undecylenate) run that for 15-20 weeks with the test ud get some very good gains 300-500mgs would be plenty of EQ. It can help with burning some fat get the vains poping more nice slow but very real dense gains. and if you wanted to put in the tren ace at the last couple weeks to help harden you up some that could work. (dont now alot about tren and dosing so not going to say) lol but this would be very good if cash is tight as primo is very hard on the wallet.

thanks
im really looking to see what i can do with what i have

so ill run the
ot 5-750 mcgms a day for 4 weeks
ill run the test c at 250mg a week for 8 weeks
how should i run the omnadren250 ? and when i have 9 amps

You could run it the same as Test C mate or double the dose up to you doe id rather go with a longer cycle at a lower does than a short cycle at a high dose (unless its short acting gear like prop)

Ok still need help on this as I'm not getting what you said. On the test. I'll run it for 8weeks at 250 the do I run the omandran after that. Say from week 8until it runs out?

This is what I'm asking

Or do I run the omnadran with the test at the same time. Say 250 test and 250 omndran. They will both be used up after 8-9 weeks

Lastly. On the oral tern. I'll be running it 4weeks. Do I then hold off 4weeks and run it again? If so. I could run the test the first 8 weeks with the first 4 weeks of tren. Then just test for 4 weeks and then tren again for 4 more weeks while I run the omndran

I have novaldex and clomid for pxt and I'll be running liv 52 the entire time

I would certainly not run oral tren again so soon after finishing the first cycle, give your liver a chance to recover.

I would run the test and omnadren together for the 9 weeks, if you start off the first week with 250mg then it should work out as a 10 week cycle.

PCT should start 18 to 21 days after your last injection as Omnadren is pretty much the same as Sustanon

thanks
exactly what i was asking

cc comes through as always

Hey CC
Here is an inventory of what I have

I just got the cabaser so Im ready to start the oral tren cycle
but here is a list and I hope you can help me put a good cycle together with this and use it to the best result

so

liv 52 2 bottles of 100 tabs
liv 52 ds 3 bottles of 60 tabs
trenbolane acetate 9 amps 100 mg each
omnadren 250 12 amps 1 ml each
e-methenolon 3 vials 1000 mg each
anabol tabs 5 mg 1000 tabs
testoxyl cypionate 250 2 vials 10 ml each
ortrexyl 250 mcg 1000 tabs
clen 40s 200 tabs
novaldex 20mg 200 tabs
clomid 50 mg 20 tabs
cabaser 1 mg 20 tabs

so what is the best use?

I would just go simple first,
I'd do Oral tren up to 3 tabs per day for 4 weeks( work up to the maximum dosage over a few days for example start off on one tab then 2 days later add another and another 2 days later add the third)

Take the Cabasar to avoid any unwanted sides, half a tablet every 4 days is more than enough.

You could add test at 250mg per week for 12 weeks if you want but thats up to you.
I would prefer to see if you get any sides from the OT alone.

Make sure you use the Liv-52 when using Oral Tren, for the first week take 2 tabs twice per day, then 1 tab twice per day for the duration of the tren cycle, I like 2 carry on with the Liv-52 for a further 3 weeks after the tren has finished.

ok well not enough test
i only have enough for 10 weeks
would you stack the omanadran with it?

say like

ot up to 750 mcg a day for 4 weeks?
test 250 a week for the 10 weeks
omandran 250 a week for 12 weeks?
cabaser 1 tab every 3-4 days
liv 52 2 a day for the duration

how does this look?

You have 12 Omnadren, so you have 12 weeks

so run the test and the omandran together right total of 500mg a week

No, Omnadren is Test run the Omnadren at 250mg per week

ok ill save the test c for another cycle or the next oral tren cycle

and as you saw i have a little primo

a little primo is no good to you, you will need to get a lot more

yep i know

how much do you think i should go for

figure im going to run a couple of ot cycles first so the primo cycle will be some time down the line

you know what i have how much more should i look to get

sorry for the newby questions im not a newb but seem to be out of it a bit

You want at least 600mg per week but it would be better to go for 800 to 1000mg per week to get the best out of it, take it for 16 to 20 weeks.

enough said
ill start ordering

thanks cc