Without Accutane
Why without Accutane?

Accutane has been connected not only to the short term side effects that we all know of (stomach discomfort, dry skin/eyes/lips, liver effects, joint pain) but also to severe, potentially permanent side effects such as: joint pain, Crohn's Disease, Irritable Bowel Syndrome, depression, sexual side effects, dry skin, nosebleeds, reduced healing ability, etc. Accutane is structurally similar to Vitamin A, and most of these effects are related to Vitamin A toxicity. Research Accutane side effects, and Vitamin A toxicity before getting on Accutane. Accutane should be the complete last resort for acne.

Steroids and Acne
Unfortunately, any amount of steroids is most likely going to increase acne especially if you are predisposed to it. Some hormones will affect people differently, some get more acne on tren, some test, some NPP, etc. Regardless of E2, you will get acne from steroids.

Estrogen (E2) high or low can both cause acne (usually high, but large fluctuations are no good), and acne may result even from having normal estrogen levels just due to the androgens in your system. Aim for consistent E2 levels, this will lower your chance of acne the most.

DHT and Acne
Nizoral and Head & Shoulders are supposedly good for fungal acne, although it may be hard to identify it as such though.

Ketoconazole or Nizoral are typical anti androgens. Get the benefits of stopping DHT from binding to the sebaceous gland without ingesting an anti-androgen.

Lifestyle Habits & Washing Habits
Firstly, a great resource is acne.org and it's subsequent forums and this includes much general consensus from acne groups.

Refrain from using harsh washes or activities that will increase inflammation of the skin (#1 reason for acne). This means:

Do not use alcohol, sulfates (soap), acne bead scrubs, overly drying washes. instead use gentle cleansers, (acne.org has one), sulfate free, and wash your face very lightly and splash water to wash it off. PAT to dry DO NOT scrub.

Do not touch, scrape, or pop your acne. Don't run your dirty fingers over your acne. Do not spend time pushing out plugged comedones, black heads, white heads. Do not excessively press and pop pimples that are not popping, even if the end result it pops. If it takes more than 15 seconds for it to pop, leave it alone until its ready instead: if you must, only pop pimples that are easily popped and ready with clean hands right before you wash it. A warm shower can make it easier to pop but scalding hot water may be negative to skin moisture. However it is more ideal to never pop pimples

Do not sleep on dirty bedsheets or pillow cases. Do not re wear dirty shirts, or continue wearing a gym shirt that you just worked out in. instead, shower/rinse immediately after gym and put on a clean shirt. If you go home after gym and shower that is usually fine too. Replace bedsheets 2x a week and pillow cases EOD (flipping the pillow after the day to get double use)

Do not excessively wash your skin, it leads to over-drying. If possible, wash your back/face with a gentle wash 1x a day at the max. If you need to take a second shower before bed due to general day sweat, rinsing with water and wiping with hands is completely fine.

Washing
As counterintuitive as it sounds, over washing can lead to acne. Your aim should be to maintain a certain level of stability with your skin. This means over-washing will dry out your skin and cause acne. You must completely avoid normal soap and sulfates.

Consider a salicylic acid wash or benzoyl peroxide wash (the OG proactive uses this) and using 1x a day max. If they dry out your skin stop for a couple days. Some people find success with a benzoyl peroxide wash, but I think salicylic acid is better as benzoyl peroxide is a generally better treatment for leaving on skin. Others have the opposite opinion.

Consider washing your back with no soap at all if you haven't gotten extremely dirty. Your body maintains a natural ph and good bacteria that lessen the ability for bad bacteria to colonize and from acne. Simply rinsing off and not washing at all can do wonders due to the reduced inflammation on your skin.

Treatment
This is where it gets to the good stuff.

Test all medications first in a small part of skin before dousing yourself with it. Benzoyl Peroxide and Azaelic Acid tend to be the biggest culprits of redness, as well as Differin to a lesser extent.

Adapalene (brand name Differin) is a 3rd generation retinoid that specifically targets the mechanisms that produce acne. It prevents the formation of comedones by 50-60% according to studies. Retinoids are structurally related to Vitamin A - and Accutane is a retinoid. Adapalene (Differin) is a topical retinoid and since being applied to the skin it does not absorb through the blood stream (as shown by studies significantly insignificant amounts get through). So, you're basically taking topical Accutane. Adapalene (Differin) has always been the most effective acne medication for me in permanently reducing the amount of acne I get, and after a year of diligent use in my teens I never got pimples anymore. Additionally, Adapalene (Differin) increases the efficacy of other popular acne treatments such as topical Clindamycin and Benzoyl Peroxide.

Benzoyl Peroxide 2.5% (gel version is best) - there is no evidence that stronger concentrations are better, and they generally just dry out the skin more. Benzoyl Peroxide is the holy grail of treatment because bacteria never get resistant to it. It provides an oxygen rich environment that is impossible for bacteria to live in. Issues with BP = sensitivity to sunlight, redness on skin, allergic reaction (under 5% have this) so take away = start slow when using benzoyl peroxide, EOD at first, then ED. 2x a day if your body can handle it. It also bleaches clothes, so if you put it on before putting on clothes you need to let it dry, and probably have a white t shirt/white sheets.

Topical Clindamycin: Clindamycin is a popular antibiotic, but when used topically for acne treatment it significantly boosts the efficacy of Adapalene and Benzoyl Peroxide. However, tolerance increases pretty quickly, and I only recommend using it when a breakout occurs, or for spot treatment of specific pimples. It's useful l usually sold in combination with Benzoyl Peroxide 5% but it's in your interest to get it separately because 5% Benzoyl Peroxide is over drying and this way you can regulate your tolerance to it

Curology (prescription) 4% Azelaic Acid. (precursor to Salicylic Acid) 1% Clindamycin, 4% Nicotinamide. I've read good things about this from skin care addiction but have not used myself. Studies show Nicotinamide being as effective as 1% Clindamycin without resistance.

Salicylic Acid option: a slightly weaker option than Benzoyl Peroxide, but still effective. Be sure the lotion it's mixed with is quality and you might find something useful. You might be better off finding it in pure gel. However Benzoyl Peroxide has shown in studies be more effective and the combo treatment with Differin is promising.

Jojoba Oil: widely considered the best type of oil to moisturize your skin because it is very similar to the natural oils that we produce. It's a favorite on /r/skincareaddiction

Zinc 20-50mg for 3 days after breakout you can't stay on high zinc forever, but doing this has been found to be effective. Lots of anti inflammatory properties in Zinc. 10-20mg is about a maintenance dose. It's good to use Zinc-Carnosine complex, because it has the added benefit of restoring stomach lining and reversing damage from spicy food etc. No heartburn for some.

Side Notes

Adapalene (Differin) used to be prescription only, but is now available over the counter. It also comes in a mixture formula with Benzoyl Peroxide called Epiduo, but it is still prescription only.

Clindamycin is prescription only. Benzoyl peroxide can be found anywhere. For all of these drugs you should be aiming to get the gel versions. If you go to your dermatologist and ask for them, you should probably be able to get everything that you want.

Adapalene (used first) followed by Clindamycin, and Benzoyl Peroxide, is the holy trinity of destroying acne. If using these 3 medications is causing you to get overly dry skin, you probably want to drop everything but always continue Adapalene usage as it improves your skin over time and reduces your ability to create new comedones. If you can only take Adapalene 1x a day is fine. 2x is better. It's better to use a thin layer of it everywhere (more just over-dries) if your skin is sensitive from overuse, just spot treat with it for a while but you really want to throw it on everywhere

Moisturizing
Use a non-comodegenic moisturizer. The oil you should be using on your face is Jojoba Oil. Cetaphil and CeraVe make great facial moisturizers. Use these after treatment in combination with Jojoba Oil, if Jojoba Oil is not enough.

Dietary Factors
Many people swear that cutting out Dairy reduced their acne. Considering the amount of hormone derivatives pumped into cows, it is a reasonable assumption. Since many of us are putting hormones into our body anyways, it might not matter, but most people get reduced acne from cutting out Dairy.

Cutting out Sugar & Fructose can reduce acne. Inconsistent blood sugar levels are related to acne, and high amounts of sugar provide a good environment for bacteria to proliferate. Try it out.

Eating more veggies. Try it out, it might help.

Summary
In summary, if you get anything out of it: GET ADAPALENE (DIFFERIN)! it's the most effective treatment for preventing further acne (and reducing current). It's basically topical accutane.

__________________
[email protected]
[email protected]
[email protected]
[email protected]

With Accutane
Introduction
Isotretinoin (Accutane) is primarily used to treat bad cases of cystic acne, and to help the skin more rapidly renew itself. In addition, it is used in rare cases for certain skin cancers and skin diseases. It is a type of retinoid, which is naturally found in the body in small amounts. In the USA, it’s a prescription drug, but it is sold over the counter without a prescription in many countries.

Bodybuilders who use anabolic steroids have utilized Accutane to counteract the negative effects of steroids on their skin; especially, the acne related side effects.

When other treatments fail, Accutane becomes the last resort to help combat acne issues

How it Works
Accutane works as an isomer of Vitamin A, which reduces the amount of oil released by the oil glands in the skin; this will make it difficult for acne to form and reduce it significantly. Nearly all patients achieve clearing of acne during a course, with 90% reporting ‘excellent’ results with higher dosages. Those that choose to dose low will have results with diminished side effects, but run the risk of recurrence.

Bodybuilding
Since chances of acne are increased with anabolic steroid use, and bodybuilding requires looking good (especially physique competitors), many athletes who have failed to conquer their acne with natural remedies will turn to Accutane.

It is the androgenic increases associated with steroids that will trigger increased acne. This is especially true for those genetically prone to the condition. Also, the hormonal changes can trigger acne as well, such as increased testosterone levels.

Side Effects
High doses of Accutane will result in vitamin A toxicity, which will result in both permanent and temporary side effects.

Permanent and temporary side effects such as :

Stunted growth: The FDA, in 2010, stated the drug may stop bone growth in teenagers still growing

Inflammatory bowel disease: Some studies have linked this drug to causing Crohn’s disease

Eye changes: Decreased night vision and dry eyes have been reported

Other issues like skin problems, hyperostosis, and birth defects (in pregnant women) have been reported

Psychological effects, particularly depression, seems to be a common, but that has yet to be proven in studies

Dosage
Among bodybuilders, the dosage should be conservative. Once a day dose of 10-20mg for 6-8 weeks (some need more, some need less), depending on severity, should work fine, but you can extend it necessary. Some users suggest using Accutane 10-20mg 2-3 times per week when coming off cycle or dropping to a cruise dose of Test; to prevent acne sides if you're susceptible to it. Among the general public fighting acne, a dosage of 50-150mg per day may be prescribed by their physician. It is a good idea to take the drug with a large meal.

__________________
[email protected]
[email protected]
[email protected]
[email protected]