Drostanolone propionate is used primarily by athletes who need to retain strength while losing mass. It is beneficial to runners and athletes who must remain in a certain weight class.

It has gained popularity in the bodybuilding community as a diuretic and muscle defining drug. Individuals interested in using the drostanolone propionate are those that are looking to add muscle hardness and density to their physiques, nearly always for the purpose of bodybuilding competitions.

Drostanolone propionate can increase muscle hardness and density, giving an individual a more complete appearance when competing on stage.[citation needed] However, an already rather low body-fat level is needed for it to take full effect.[citation needed] Drostanolone propionate can promote increased strength while keeping body fat the same or even lowering it, something can help to prevent muscle loss while dieting.[citation needed] This can also allow strength athletes or those athletes in sports which have weight classes to increase performance without the risk of being raised into a higher weight class or add mass that may hinder performance.

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