I inject 2.5 cc's in the quad at a time and I only feel it a bit the next day, it's not a pain, but I feel it.

usually a little bit of pain is more common when injecting in a virgin muscle, you'll feel this every new muscle you inject in.

and to ... (i'm too lazy to scroll up) that wanted to do 500 in one shot a week. that is acceptable, but one of the reasons to split it up in two shots (other then injecting less oil at a time) is to keep a more stable blood level.

more stable levels = less sides (this applies to all compounds)

And scotty, I would try a difference muscle group. I find the glutes to be the best to inject, a little awkward the first few times you inject them. and not all test e's are created equal, there are several reasons why, it could just be the type of oil it's in.