I think all the risk's spoken of here can't really be controlled by dose. Of course the higher dose put's you at a higher risk but I think most people that have high bp/cholesterol or impotence are predisposed to have them anyways. I know friends of mine that only ran test cypionate for 10 weeks at 250mg per week and are now impotent but I can run test at 2g/week with some other compound at 600mg/week (prob tren) with absolutely no ill side effects. Sure my bp rises and so does my cholesterol but about 2 weeks after pct all my levels are in the normal range.