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Cornish_Celt · #3 (**permalink**) 03-31-2010, 10:02 AM

Practical Considerations

Given all of this information, there are nonetheless more things to know before you undertake your first DNP cycle. The following tips and tricks gathered from personal experience and consultations with users are presented for your aid:

Aim a fan at your head at night. Your head is the most precious thing on your body and is a prime site for heat loss. Any air flowing over it will aid in cooling via convection.
Wash your bedding daily. It is a good idea to have some spare pillowcases on hand, if nothing else. Most likely, you will be sweating profusely while you sleep, and this will make your bed smell as enticing as a locker room. Cleanliness is also essential in the prevention of disease, not to mention the fact that you are breathing out DNP "fumes" all night and they collect on your bedding.
Prevention of disease goes beyond washing your clothes, and includes all of the normal precautions that you would make to avoid infection, although in a more exaggerated way. DNP depletes your body of energy needed to battle pathogens and weakens your immune system, leaving you ripe for infection and incapable of fighting off most diseases once they have taken hold.
This is rather intuitive, but be certain to wear loose, light clothing, preferably of a light color.
Similarly intuitive is the desire to remain in a cool area … be CERTAIN not to overheat.
Proper hydration is necessary – People have consumed up to 8 liters of water per day. Glycerol specifically aids in muscle hydration, so its use may be very important, particularly when considering that muscle cells in even a semi-dehydrated state are prime sites for catabolism.
Cardiovascular work while on DNP – This is a strange issue that is asked about regularly, but i am undecided in the direction to take and generally recommend that the user decide for themselves. My personal preference is to do cardio with a fan focused on me for 30-35 minutes at a relatively high intensity. This is an area for personal preference; barring other considerations, just see if you can handle it or not and go from there. Always be ready to stop if you feel yourself getting extremely overheated or weak.
Diet - One may wonder why this issue receives such limited attention; after all, most methods of fat loss require a restrictive diet of some nature. However, there is no set diet that one must use to achieve good results with dinitrophenol, only certain factors that allow the user to decide intelligently how to eat:
Insulin - DNP blunts the effects of insulin; this is a huge boon for dieters because insulin blocks lipolysis and causes the storage of adipose tissue. This means that carbohydrate intake does not need to be strictly limited, although it should stay reasonable for optimal results.

Body Temperature and Comfort - A general guideline is that the more carbohydrates eaten, the hotter the user will get while on DNP. Similarly, overfeeding also produces extreme heat; any excess calories are thrown off as heat quite readily. For this reason, along with certain hormonal factors, Duchaine espouses an Isometric diet while on DNP, and I have followed this personally with good results.

CKD's - These are extremely impractical while on a cyclical ketogenic diet (CKD), and are especially dangerous. This brings up blood glucose considerations; it is important to try to maintain relatively stable, or at least not severely depressed, blood glucose levels. If this guideline is not followed, the user may experience blurred vision and/or extreme fatigue possibly augmented by fainting or lightheadedness.

Anabolic rebound effect – Dan Duchaine said regarding DNP, which at the time, seemed impossible. But people have experienced this phenomenon, and it indeed happens. Possible causes include, but are not limited to, either an anabolic effect from glycogen supercompensation-induced cellular expansion, or due to increased mitochondrial density. Increased mitochondrial density is an adaptive mechanism of the body and takes place surprisingly quickly in the presence of an uncoupler such as DNP (or anything else that inhibits oxidative phosphorylation). Whatever the mechanism of the anabolic rebound effect may be, the user can expect to gain about 5-7 pounds of intramuscular water or muscle and lose about the same amount of subcutaneous and intraperitoneal water within a week after their last DNP dose. This is probably the most pleasant aspect of using DNP; the user not only experiences unrivaled fat loss, but also enjoys a fair amount of hypertrophy without any other supplements or drugs. Muscle retention, and possibly gain, is improved with careful attention to several previously discussed considerations such as proper hydration and intelligent cycling.

Conclusion

Currently, DNP is the most powerful weapon against fat loss in the bodybuilder's arsenal; however, this does not necessarily mean that it is right for everyone or is by any means safe. The possibility also exists that PGF2 may be better for some people, particularly when taking the fact that it may kill fat cells into consideration. However, the guidelines given here will allow the user unrivaled fat loss, and will do so quite safely provided that precautionary measures are taken. While certainly quite dangerous, it is nonetheless the most effective tool available today for the loss of bodyfat.